SportsLine's model has simulated San Francisco vs. Detroit on Monday Night Football 10,000 times and revealed its MNF picks ...

There was concern that Detroit Lions running back David Montgomery would miss the remainder of the season when he suffered a ...

Lions vs. 49ers predictions and expert picks for Monday Night Football on December 30. Expect a big night from Jauan Jennings ...

SportsLine expert Jimmie Kaylor shares his Week 17 NFL DFS picks, stacks, sleepers, rankings, values, lineups and player pool ...

With the high-scoring contest against the 49ers, the Lions clinched their fifth game this season with 40 points and 0 ...

The Detroit Lions have two wide receivers and two running backs with more than 1,000 scrimmage yards, the most in NFL history ...

The Detroit Lions continue to set franchise and league marks across the board. Their latest re-writing of the NFL history ...

The Detroit Lions will keep pushing for the top seed in the NFC playoff bracket when they visit the San Francisco 49ers (+3.5 ...

Here is where the San Francisco 49ers sit in the latest NFL power rankings heading into a "Monday Night Football" matchup ...

Week 17 ends with a Monday Night Football showdown between the Lions and the 49ers.  While San Francisco is out of playoff contention after an injury riddled se ...

What channel is Monday Night Football on? How to watch NFL Week 17 game between Detroit Lions, San Francisco 49ers on TV, ...

In other words, the 49ers’ disappointment is getting worse as the season carries on. San Francisco has already lost stars in ...