The San Francisco 49ers picked up their first loss of the season, falling 23-17 to the Minnesota Vikings in Week 2. A special teams error, two turnovers (interception and fumble) and two turnovers ...

The San Francisco 49ers have one of the most well-built rosters in football. San Francisco made a run to the Super Bowl last season, although it ended up losing to the Kansas City Chiefs.

49ers star tight end George Kittle was not in attendance for Thursday's practice session. According to ESPN's Adam Schefter, Kittle is experiencing tightness in his hamstring. The 49ers are taking ...

The San Francisco 49ers will travel to Los Angeles in Week 3 to face the Rams at SoFi Stadium. The matchup is set to kick off at 1:25 p.m. PT on Sunday, September 22. Here are all the ways to ...

The loss to the Minnesota Vikings is getting worse for the San Francisco 49ers. Star wide receiver Deebo Samuel sustained a calf strain in the game and is expected to be out for a "couple weeks ...

The San Francisco 49ers recently navigated a tumultuous period involving wide receiver Brandon Aiyuk, who initially sought a trade but ultimately secured a new contract with the team. The ...

Just two games into the season, the Rams (0-2) are approaching desperate times as they prepare to face the San Francisco 49ers (1-1) Sunday afternoon at SoFi Stadium. The list of issues thus far for ...

In light of these injuries, Shanahan has indicated that the 49ers will strive for cohesive execution, despite the changes in their lineup. "The absence of two key playmakers pushes us to find ...

The San Francisco 49ers are at risk of being without another star offensive player for Week 3. Tight end George Kittle is experiencing hamstring tightness and did not practice Thursday ...

The 49ers reportedly checked in on multiple potential replacements for Brandon Aiyuk in the wake of the uncertainty surrounding the wide receiver this offseason. Before San Francisco ended their ...