When the gene that codes for EGFR has a mutation, it affects the way this protein works, causing cancer. There are many types of EGFR mutations. The EGFR protein lives in the cell membrane with ...

Researchers used base and prime editing to uncover new EGFR gene mutations that affect cancer progression and drug resistance ...

The work detailed each of the four types of mutation, outlining how known mutations impact drug resistance, and also highlighting new DNA mutations that could be explored further. The results also ...

If it is caught early and can be removed fully with surgery, the specific type of cancer and mutations it has won’t change your treatment or outlook. But most lung cancers aren’t caught at ...

All cancer mutations that cause drug resistance fall into one of four categories. New research has detailed each type, helping to uncover targets for drug development and identify potential ...

The types of SGs vary depending on the plant species ... are absent or dysfunctional due to a genetic variation called mutation, it leads to considerable changes in the starch properties.

Certain types of cancer are common in the United States and are often influenced by lifestyle choices. For example, skin ...

Learn about research at MSK that finds obesity can influence driver mutations that produce specific subtypes of cancers, ...

Structural studies classified common TP53 mutations into two types: contact mutations, which affect DNA-binding amino acids, and structural mutations, which destabilize the protein’s DBD.

One reason for this under-exploration may be the challenge of selectively recognizing an oncogenic mutation while sparing the wild-type (WT) counterpart.” Koide et al’s studies revolve around ...