Single-Cell Multiomics Enables High-Resolution Vector Copy Number Profiling in CAR-T Therapies

Mission Bio, the leader in single-cell multiomics, published research in Molecular Therapy Advances showing that their ...

Single-vesicle profiling could push liquid biopsies toward everyday clinical use

Extracellular vesicles, or EVs, are tiny membrane-bound particles released by nearly all cells. They carry proteins, RNA, ...
ascopubs.org

Artificial intelligence (AI)-powered evaluation of protein drug-targetability through subcellular-level expression profiling from immunohistochemistry (IHC) images.

The first-in-human phase 1/2 study of TSN1611, a highly selective KRAS G12D inhibitor, in patients with advanced solid tumors. Seizure-related homolog 6 (SEZ6) expression and ctDNA methylation ...

CAMP4 Therapeutics Preprints Pioneering Study on Regulatory RNA Profiling and Gene Upregulation

Capture-seq, CAMP4 has assembled what it believes to be the largest catalog of regRNAs ever compiled, uncovering thousands of previously undiscovered regRNAs in human cells New research enables the ...
ascopubs.org

Multiomic Characterization and Molecular Profiling of Nuclear Protein in Testis Carcinoma

Comprehensive Genomic Assessment of Advanced-Stage GI Stromal Tumors Using the Japanese National Center for Cancer Genomics and Advanced Therapeutics Database We analyzed the genomic and immune ...
EurekAlert!

New proteomics method enables sensitive identification of ligand-binding proteins and their binding sites in complex system

In a study published in Nature Methods, a research group led by Prof. YE Mingliang from the Dalian Institute of Chemical Physics of the Chinese Academy of Sciences (CAS), collaborating with Prof. LUO ...
eLife

Evidence of off-target probe binding affecting 10x Genomics Xenium gene panels compromise accuracy of spatial transcriptomic profiling

Computational assessment identifies probe binding errors in a widely used commercial platform for spatial transcriptomics.