Gene regulation is the process by which cells control the expression of their genes, determining when, where, and to what extent each gene is expressed. It is a fundamental mechanism that allows cells ...

Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

“This is the first detailed study of how and where ORC regulates epigenetics and gene expression in human cells,” said Anindya Dutta, Ph.D., leader of the study and chair of the University of Alabama ...

A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem ...

In biology classrooms, we often learn that genes are transcribed into mRNA, which is then translated into proteins—a tidy, linear process. But gene expression in living cells is far more intricate, ...

From the TATA box to alternative splicing and noncoding RNAs, scientists are uncovering the intricate choreography that controls gene expression. These molecular mechanisms determine when, where, and ...

A study reveals chromatin moves in constrained or freer patterns, shaping how genes contact regulatory elements and repair ...

Professor Carsten Carlberg has published a comprehensive new textbook, Gene Regulation and Epigenetics: How Science Works, presenting the current understanding of gene regulation and epigenomics.

KYOTO – An international team of researchers has taken an important step toward understanding how gene expression is controlled across the human genome. A new study has comprehensively analyzed ...

Cellular homeostasis and stress response are tightly coordinated processes involving a complex interplay between signaling ...

From DNA’s tightly packed chromatin to the precise on/off switches in regulatory sequences, scientists are uncovering how cells fine-tune gene expression. New research reveals surprising roles for ...