Our DNA is constantly being packed and unpacked. And there is a good reason for this: depending on its packing state, it performs different functions in the cell nucleus. For most of its life – this ...

Different types of cell division failure shape whether duplicated cells survive, remain stable, or lead to cancer.

Model for ORF1p-RNP formation and DNA recognition. ORF1p forms homo trimers and higher-order oligomers that can bind to DNA but have a clear preference for RNA. Credit: Sarah Zernia et al Model for ...

If DNA bridges remain between chromosomes after cell division, chromosome segregation can be disrupted, leading to genetic instability and increasing the risk of cancer. Researchers at UNIST and the ...

Many cellular functions in the human body are controlled by biological droplets called Liquid-Liquid Phase Separation (LLPS) droplets. These droplets, made of soft biological materials, exist inside ...

If measured from beginning to end, the DNA in our cells is too long to fit into the cell’s nucleus, explaining why it must be constantly folded and packaged. When it is time for cell division, and the ...

Researchers at the Centre for Genomic Regulation (CRG) reveal that metabolic enzymes known for their roles in energy production and nucleotide synthesis are taking on unexpected "second jobs" within ...

Before a cell can divide, it has to precisely duplicate its entire genetic information. However, the DNA in the cell exists as part of a DNA-protein complex known as chromatin. For this purpose, the ...

DNA does not float freely in the cell. Instead, it is wrapped around histone proteins to form structures called nucleosomes.

(Nanowerk News) If measured from beginning to end, the DNA in our cells is too long to fit into the cell’s nucleus, explaining why it must be constantly folded and packaged. When it is time for cell ...