President-elect Donald Trump announced that Susie Wiles, who managed his reelection campaign, would become his chief of staff. It makes Wiles the first woman to hold the role, the most senior political appointee in the White House with significant power and influence.

Susie Wiles is set to take on one of the most important — and arguably unforgiving — jobs in Washington as President-elect Trump’s chief of staff. Those who know Wiles and have worked with her during her years as a Republican operative in Florida and ...