The wide receiver took a few knocks in the defeat to the Lions on New Year’s Eve. He missed all of the Niners' practices last week.

The San Francisco 49ers entered their Week 18 finale on the road against the Arizona Cardinals with several starters ruled out. Quarterback Brock Purdy, receiver Deebo Samuel and cornerback Deommodore Lenoir were all ruled out with injuries.

Wide receiver Deebo Samuel, quarterback Brock Purdy and cornerback Deommodore Lenoir are all listed as ‘out’ for the team’s Week 18 matchup with the Arizona Cardinals. Tight end George Kittle is also ‘questionable.’

The San Francisco 49ers entered the 2024 season with high hopes, aiming to bounce back after their second Super Bowl loss during the Kyle Shanahan

San Francisco 49ers wide receiver Deebo Samuel is officially listed as ‘out’ on the team’s Week 18 injury report, meaning his four-touch, 17-yard, one-touchdown performance against the Detroit Lions in Week 17 could be his last in red and gold.

The 49ers will wrap up a massively disappointing season without a number of starters when they face the Cardinals in Week 18.

Like the players declared out, Flannigan-Fowles did not practice all week. Brown was limited Friday after being limited Wednesday and out Thursday. Kittle did not practice Wednesday and was limited the final two days. McKivitz was limited Friday after not practicing Wednesday and Thursday.